Job Description
This application is for a 12-week internship role from June - August 2025. Resume review begins in January 2025.
The Bioassays and High-Throughput Screening (BHTS) group is responsible for assay optimization efforts for either routine project support to monitor a material's (biologics or small molecules) effects on specific targets and pathways or execute in-house large-scale screening of our internal compound library for early program lead identification efforts. This is largely accomplished using our automation systems and robotics platform. This project will focus on a smaller collection of small molecules with screening for compounds' effects on a neurobiology target in a cell-based assay system based on a Nano-Luciferase Reporter platform.
The BHTS group is within the Biotherapeutic & Medicinal Sciences department. The primary goal of BHTS is to support early drug discovery efforts across all the therapeutic indications that Biogen focuses on. Our work informs the discovery pipeline and drives the earliest portions of Research and Discovery efforts at Biogen.
Position Description
- Tissue culture techniques to support cell-based assays
- Learn instrument use/management, QC of liquid handlers, and software for data analysis and interpretation of experimental results
- Execute the day-to-day process of high throughput screening with significant use of our group's HighRes Robotics system
- Complete a small library of compound screening with data reported to the database and delivered to the project team
Example projects may include:
- Use of volume validation instruments to QC either/both of PRIME and Agilent Bravo liquid handlers. This includes creating a template to track the results and distribute to the group
- Maintain cultures of human cells
- Assay optimization efforts to support internal HTS execution
- Learn software used to analyze large data sets and understand what statistical outcomes drive assay validation/robustness
Qualifications
- Pipetting by hand with micro-pipettes, tissue culture experience a plus
- Minimal experimental design and execution
To participate in the Biogen Internship Program, students must meet the following eligibility criteria:
- Legal authorization to work in the U.S.
- At least 18 years of age prior to the scheduled start date
- Be currently enrolled in an accredited community college, college or university
Education
- Currently matriculating undergraduate with a major in Biology/Biochemistry/Cell Biology/Biotechnology/Chemistry
Location
- This role is on-site in Cambridge, MA
Additional Information
Why Biogen?
We are a global team with a commitment to excellence, and a pioneering spirit. As a mid-sized biotechnology company, we provide the stability and resources of a well-established business while fostering an environment where individual contributions make a significant impact. Our team encompasses some of the most talented and passionate achievers who have unparalleled opportunities for learning, growth, and expanding their skills. Above all, we work together to deliver life-changing medicines, with every role playing a vital part in our mission. Caring Deeply. Achieving Excellence. Changing Lives.
At Biogen, we are committed to building on our culture of inclusion and belonging that reflects the communities where we operate and the patients we serve. We know that diverse backgrounds, cultures, and perspectives make us a stronger and more innovative company, and we are focused on building teams where every employee feels empowered and inspired. Read on to learn more about our DE&I efforts.
All qualified applicants will receive consideration for employment without regard to sex, gender identity or expression, sexual orientation, marital status, race, color, national origin, ancestry, ethnicity, religion, age, veteran status, disability, genetic information or any other basis protected by federal, state or local law. Biogen is an E-Verify Employer in the United States.
