Job Description

Our company SSF has a position open for a High-Throughput Purification (HTP) Senior Scientist within the Discovery Chemistry Department located at our South San Francisco, CA site. The successful candidate will be highly independent and detail-oriented, with an analytical mindset and thrives in a fast-paced, collaborative team environment. The candidate will be responsible for developing chromatographic methods and provide routine and specialized purification support and reporting for a range of modalities at varying scales, leveraging a variety of analytical techniques, novel instrumentation, and custom informatics tools. Specific responsibilities will include:

Job Responsibilities:

• Be an integral part of our company's growing High-Throughput Purification team and work withchemists, biologists,and engineers to advanceourdrug discovery pipeline

• Operate state of the art analytical and purification instrumentation (HPLC, UPLC, SFC, Hi-Res MS, 2D-LC) to characterize and purify lead candidates from small molecules to peptides and bioconjugates

• Proactively develop specialty separations, and optimize related chromatographic methods for individual programs

• Help identify, evaluate, and recommend novel instrumentation and workflows to achieve early-stage project goals

• Collaborate with automation teams to design and implement machine learning software tools and robotics to automate laboratory workflows and processes

• Oversee overall instrument performance and health, perform basic troubleshooting, and schedule preventative maintenance and repair with key vendors

• Contribute to our external scientific presence through presentations and the writing of technical documents, scientific manuscripts, etc.

Qualifications:

Education:

• Bachelor's (with 7+ years), Master's (with 4+ years) or Ph.D. in Analytical Chemistry, Chemical Engineering, Biochemistry or related field with relevant experience listed below

Required Experience and Skills:

• Hands-on research experience in a pharmaceutical/biotech setting and familiarity with Waters, ThermoFisher, and/or Agilent LC-MS instrumentation, relevant software platforms, subsequent data analyses and interpretation

• Demonstrated ability to independently develop and perform critical experiments in a fast-paced, dynamic environment

• Self-motivated with high attention to detail, ability to rapidly analyze, summarize and present data and significant conclusions

• Excellent organizational skills with ability to meet deadlines and prioritize work on multiple projects

• Uncompromising integrity and proven success working in a high-performing, diverse, and inclusive team environment

• Ability to communicate clearly and build collaborative relationships is essential

Preferred Experience and Skills:

• Data science and/or computer programming experience with knowledge of AI/ML software tools for predictive analytics to improve decision-making

• Prior exposure to high-throughput lab operations, automation, and compound array purification

#EligibleforERP

Current Employees apply HERE

Current Contingent Workers apply HERE

US and Puerto Rico Residents Only:

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We are an Equal Opportunity Employer, committed to fostering an inclusive and diverse workplace. All qualified applicants will receive consideration for employment without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status, or other applicable legally protected characteristics. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:

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We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another's thinking and approach problems collectively.

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U.S. Hybrid Work Model

Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, Monday - Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence.This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as "remote".

The Company is required to provide a reasonable estimate of the salary range for this job in certain states and cities within the United States. Final determinations with respect to salary will take into account a number of factors, which may include, but not be limited to the primary work location and the chosen candidate's relevant skills, experience, and education.

Expected US salary range:

Available benefits include bonus eligibility, long term incentive if applicable, health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and sick days. A summary of benefits is listed here.

San Francisco Residents Only:We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance

Los Angeles Residents Only:We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles' Fair Chance Initiative for Hiring Ordinance

Search Firm Representatives Please Read Carefully
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

Employee Status:

Relocation:

VISA Sponsorship:

Travel Requirements:

Flexible Work Arrangements:

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Requisition ID:R331087