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Children's Hospital of Philadelphia (CHOP) offers countless ways to change lives. Our diverse community of more than 20,000 Breakthrough Makers will inspire you to pursue passions, develop expertise, and drive innovation.

At CHOP, your experience is valued; your voice is heard; and your contributions make a difference for patients and families. Join us as we build on our promise to advance pediatric care-and your career.

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CHOP is committed to building an inclusive culture where employees feel a sense of belonging, connection, and community within their workplace. We are a team dedicated to fostering an environment that allows for all to be their authentic selves. We are focused on attracting, cultivating, and retaining diverse talent who can help us deliver on our mission to be a world leader in the advancement of healthcare for children.

We strongly encourage all candidates of diverse backgrounds and lived experiences to apply.


A Brief Overview

The Genomic Diagnostic Laboratory (GDL) of the Children's Hospital of Philadelphia is seeking a highly motivated Supervisory Bioinformatics Scientist to manage our Bioinformatics team consisting of Bioinformatics Scientists, Bioinformatics Engineers, and RIA Programmers. This is an exciting opportunity to join our laboratory where we use a wide variety of molecular and cytogenetic test methodologies to provide accurate, timely diagnostic testing that has a direct impact on patient care. The team also supports cutting edge R&D efforts including new clinical test development and clinical research.

The Supervisory Bioinformatics Scientist is a key member of the leadership team in the GDL, collaborating with other lab leaders including the Director of Bioinformatics, clinical directors, managers, and supervisors). The successful candidate will have a strong human genetics, bioinformatics, and management background that will be applied to training, clinical work, R&D, and troubleshooting. Good documentation practices as well as strong organizational and communication skills are essential. Job responsibilities include scheduling work duties, providing semi-annual performance reviews, assuring that all accreditation requirements are in full compliance, and participating in quality improvement initiatives. We seek a leader who has an interest in strategic planning to develop and improve our bioinformatics pipelines and other tools to support our expanding test menu. This position can be worked fully on-site at our campus in Philadelphia, PA, or as a hybrid role with an expectation of on-site presence at least once a week, and additional on-site presence possible based on the needs of the lab.

In addition to many of the subject matter expert responsibilities of the Principal Bioinformatics Scientist, the Supervisory Bioinformatics Scientist will also:

• Build and supervise a team responsible for the architecture, development, testing and production rollout of integrated biomedical data resources and applications.
• Balance competing priorities and resource allocation across a portfolio of matrixed projects and collaborations.
• Promote common standards and best-practice use of multiple technologies to create innovative solutions that have a high impact on data-intensive clinical and translational research.
• Serves as the data integration team lead on larger complex projects that include informatics, clinical and translational researchers.
• Propose staffing plans for multi-year strategic data resource initiatives.
• Train, mentor, and hold junior staff accountable to the results of modern technology development methodologies such as code test coverage, continuous integration, monitoring.
• Educate staff, students, and trainees (fellows, post-docs) on appropriate staffing and expertise levels for application of data integration methods in the clinical and translational research environment.

What you will do

• A Supervisory Bioinformatics Scientist functions as both subject matter expert and team manager. The responsibilities echo those of a Principal Bioinformatics Scientist, but include direct supervision of team members and projects. A Supervisory Bioinformatics Scientist will:
• Directly lead and mentor junior staff in a direct supervisory capacity.
• Guide and develop the skills and expertise of junior staff
• Build project budgets by estimating time and effort costs
• Hold data integration and technical teams accountable to high-level project goals and timelines, mapping detailed project plans into these timelines.
• Recruit, hire, and retain a focused team of any of Bioinformatics Scientists, Bioinformatics Engineers, and Bioinformatics Programmers.
• Provide bioinformatics academic and thought leadership for joint collaborations with CHOP PIs.

Education Qualifications

• Master's Degree Required
• Doctorate Bioinformatics, Computational Biology, Computer Science, Information Science, Informatics, Biomedical Engineering, Biological Science or a related discipline Preferred

Experience Qualifications

• At least seven (7) years Experience in bioinformatics analysis, bioinformatics database development, bioinformatics database administration, bioinformatics data management, or related discipline, with progressively more complex projects in a biomedical science or healthcare environment. Required
• At least one (1) year Small team supervisory experience. Required

Skills and Abilities

• Experience in bioinformatics and statistical data analysis on highly dimensional data types such as derived from genomics and observational clinical or human subjects research data.
• Expert knowledge of relational database management systems such as PostgreSQL, MySQL, Oracle required.
• Expert knowledge of bioinformatics applications and algorithms.
• Expert knowledge of one or more of the following required: Python/Django, R, Perl, Scala, Ruby or other scripting languages.
• Expert biological domain knowledge.
• Must exhibit excellent oral, presentation, and written communication skills.
• Experience with source code management, application development, and project lifecycle management.
• Project management experience of complex matrix projects required.
• Proficiency in the areas of bioinformatics analysis, statistical modeling, data integration, and bioinformatics thought leadership in the larger biomedical community.

To carry out its mission, CHOP is committed to supporting the health of our patients, families, workforce, and global community. As a condition of employment, CHOP employees who work in patient care buildings or who have patient facing responsibilities must be fully vaccinated against COVID-19 and receive an annual influenza vaccine. Learn more.

Employees may request exemptions for valid religious and medical reasons. Start dates may be delayed until candidates are immunized or exemption requests are reviewed.

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